Description

(R)-Indoline-2-Carboxylic Acid Ethyl Ester is a high-value chiral building block and intermediate of significant importance in modern synthetic organic chemistry. Its core value lies in its utility as a precursor for the synthesis of complex, biologically active molecules, particularly in the pharmaceutical sector. This compound is primarily needed by research institutions and manufacturers engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of drug candidates, particularly those targeting neurological and cardiovascular diseases.
• Asymmetric Synthesis: Used as a starting material or auxiliary in catalytic asymmetric reactions to introduce stereochemical complexity.
• Agrochemical Research: Serves as a building block for developing novel herbicides, fungicides, and insecticides with specific chiral activity.
• Ligand and Catalyst Development: Employed in the preparation of novel chiral ligands and organocatalysts for synthetic applications.
• Peptidomimetics and Proline Analogs: Useful in the design and synthesis of peptidomimetic compounds and non-natural amino acid derivatives.
• Fine Chemical Synthesis: A versatile intermediate for the custom synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	(R)-Indoline-2-Carboxylic Acid Ethyl Ester
CAS No.	83212-48-0
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	(R)-Ethyl Indoline-2-carboxylate; (R)-1,2-Dihydroindole-2-carboxylic Acid Ethyl Ester; (2R)-2,3-Dihydro-1H-indole-2-carboxylic Acid Ethyl Ester; (R)-2-Carbethoxyindoline; D-Indoline-2-carboxylic Acid Ethyl Ester; (R)-Indoline-2-carboxylate; Ethyl (R)-indoline-2-carboxylate
EINECS	Contact for details

Quality Control

Our (R)-Indoline-2-Carboxylic Acid Ethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and pharmaceutical development. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials. This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.