Description

Dl-Valine-2,3-D2 CAS NO 83181-79-7 is a deuterium-labeled isotopologue of the amino acid DL-valine, specifically deuterated at the 2 and 3 positions. This stable isotope-labeled compound is essential for advanced research and development, providing a critical tool for precise metabolic and pharmacokinetic studies. It is primarily utilized by pharmaceutical researchers, analytical chemists, and manufacturers of diagnostic reagents who require high-purity, isotopically labeled standards for mass spectrometry and NMR spectroscopy.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a critical quantitative reference in LC-MS and GC-MS analysis for drug metabolism and pharmacokinetics (DMPK) studies.
• Metabolic Pathway Tracing: Used as a stable isotope tracer to investigate amino acid metabolism, protein synthesis, and related biochemical pathways in biomedical research.
• NMR Spectroscopy Solvent: Acts as a deuterated agent in nuclear magnetic resonance spectroscopy for structural analysis and reaction monitoring.
• Pharmaceutical Reference Standard: Employed in the quality control and method development for amino acid-based pharmaceuticals and nutraceuticals.
• Diagnostic Reagent Manufacturing: A key component in the production of advanced diagnostic kits and assays for clinical laboratories.
• Isotope Dilution Analysis: Enables highly accurate quantification of valine and its derivatives in complex biological and chemical matrices.

Basic Information

Product Name	Dl-Valine-2,3-D2
CAS No.	83181-79-7
Molecular Formula	C5H9D2NO2
Molecular Weight	119.16 g/mol
Synonyms	(±)-2-Amino-3-methylbutanoic-2,3-d2 acid; DL-Valine-d2; 2,3-Dideuterio-DL-valine; DL-2-Amino-3-methylbutyric-2,3-d2 acid; Valine-2,3-d2 (racemic); Racemic Valine-2,3-d2; (RS)-Valine-2,3-d2; 2-Azaniumyl-3-methylbutanoate-2,3-d2
EINECS	Contact for details

Quality Control

Our Dl-Valine-2,3-D2 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR and mass spectrometry, to confirm isotopic enrichment, chemical purity, and identity. We provide comprehensive Certificates of Analysis (COA) detailing all specifications, ensuring traceability and compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.