Description

1H-Indole-1-Pentanoic Acid, 2-Carboxy-2,3-Dihydro-Alpha,γ-Dimethyl -δ-Oxo-, (2S-(1(Alphas*,Gammas*),2R*))- is a high-purity, stereochemically defined indole derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated chiral building block, enabling the construction of complex molecular architectures with precise stereochemical control. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by academic institutions conducting cutting-edge chemical research.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the creation of novel, high-efficacy pesticides and herbicides where specific stereochemistry is crucial for biological activity.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development of new catalytic systems for stereoselective transformations.
• Natural Product Analog Synthesis: Employed in the synthetic studies of complex indole alkaloids and their biologically active analogs.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.
• Material Science Research: Potential precursor for specialty polymers or organic electronic materials with unique optoelectronic properties derived from the indole core.

Basic Information

Product Name	1H-Indole-1-Pentanoic Acid, 2-Carboxy-2,3-Dihydro-Alpha,γ-Dimethyl -δ-Oxo-, (2S-(1(Alphas*,Gammas*),2R*))-
CAS No.	82950-75-2
Molecular Formula	C₁₆H₁₉NO₅
Molecular Weight	305.33 g/mol
Synonyms	(2S,2'R)-2-Carboxy-2,3-dihydro-α,γ-dimethyl-δ-oxo-1H-indole-1-pentanoic acid; 2-Carboxy-2,3-dihydro-α,γ-dimethyl-δ-oxo-1H-indole-1-pentanoic acid, (2S-(1(α*,γ*),2R*))-; 1H-Indole-1-pentanoic acid, 2-carboxy-2,3-dihydro-α,γ-dimethyl-δ-oxo-, [2S-[1(α*,γ*),2R*]]-; (2S,1'R)-α,γ-Dimethyl-δ-oxo-2,3-dihydro-1H-indole-1,2-dipentanoic acid; Stereoisomer of indole-dicarboxylic acid derivative; Chiral indole pentanoic acid derivative.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We adhere to a cGMP-compliant quality management system suitable for pharmaceutical development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.