Description

(S)-1-Acetyl-2,3-Dihydro-1H-Indole-2-Carboxylic Acid CAS NO 82950-72-9 is a high-purity chiral building block and key synthetic intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a versatile precursor for constructing complex molecules with defined stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) and other fine chemicals. This compound is essential for research and production teams in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for their synthetic routes.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel drug candidates, particularly in the development of enzyme inhibitors and receptor modulators.
• Agrochemical Research: Used in the design and production of advanced pesticides and herbicides where specific stereochemistry impacts biological activity.
• Asymmetric Synthesis: Serves as a starting material or intermediate in catalytic asymmetric reactions to create enantiomerically pure compounds.
• Peptidomimetics & Bioactive Molecule Construction: The indoline carboxylic acid scaffold is valuable for designing peptide analogs and other bioactive molecules.
• Academic & R&D Laboratories: Employed in medicinal chemistry research for structure-activity relationship (SAR) studies and novel compound library generation.
• Fine Chemical Production: Used in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	(S)-1-Acetyl-2,3-Dihydro-1H-Indole-2-Carboxylic Acid
CAS No.	82950-72-9
Molecular Formula	C11H11NO3
Molecular Weight	205.21 g/mol
Synonyms	(S)-1-Acetylindoline-2-carboxylic Acid; (2S)-1-Acetyl-2,3-dihydro-1H-indole-2-carboxylic Acid; (S)-1-Acetyl-2-indolinecarboxylic Acid; (S)-2-Carboxyindoline-1-acetic Acid; 1-Acetyl-(2S)-indoline-2-carboxylic Acid; (S)-Indoline-2-carboxylic Acid, 1-acetyl-; (S)-N-Acetyl-2-carboxyindoline; 82950-72-9
EINECS	Contact for details

Quality Control

Our (S)-1-Acetyl-2,3-Dihydro-1H-Indole-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical and research applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.