Description

(S)-Indoline-2-Carboxylic Acid Ethyl Ester CAS NO 82923-81-7 is a high-purity chiral building block of significant importance in asymmetric synthesis. This compound serves as a key intermediate for constructing complex molecules with defined stereochemistry, which is critical for biological activity. It is primarily needed by pharmaceutical R&D and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of various drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Catalysis Ligand Precursor: Used in the preparation of chiral ligands and organocatalysts for enantioselective transformations.
• Agrochemical Synthesis: Serves as a building block for creating enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Academic & Industrial Research: Employed in medicinal chemistry programs and process chemistry development for route scouting and optimization.
• Peptidomimetics & Bioactive Molecule Construction: The indoline scaffold is valuable for designing protease inhibitors and other biologically active compounds.

Basic Information

Product Name	(S)-Indoline-2-Carboxylic Acid Ethyl Ester
CAS No.	82923-81-7
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	(S)-Ethyl Indoline-2-carboxylate; (S)-2-Carbethoxyindoline; Ethyl (S)-2,3-Dihydro-1H-indole-2-carboxylate; (S)-1,2,3,4-Tetrahydro-2-quinolinecarboxylic Acid Ethyl Ester; (S)-Indoline-2-carboxylic Acid Ethyl Ester; L-Indoline-2-carboxylic Acid Ethyl Ester; (2S)-2,3-Dihydro-1H-indole-2-carboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our (S)-Indoline-2-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.