Description

(S)-(-)-Indoline-2-Carboxylic Acid Hydrochloride is a high-purity chiral building block and intermediate of significant importance in asymmetric synthesis. This compound matters because its defined stereochemistry is crucial for imparting specific biological activity in advanced pharmaceutical agents. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly for central nervous system (CNS) targets and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of potent, biologically active molecules, including protease inhibitors and receptor modulators.
• Asymmetric Synthesis: Used as a starting material or resolving agent for constructing complex molecules with high enantiomeric purity.
• Chemical Research: Serves as a valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Agrochemical Development: Potential intermediate in creating chiral active ingredients for crop protection products.
• Catalyst Ligand Synthesis: Can be utilized to develop novel chiral ligands for asymmetric catalysis.

Basic Information

Item	Details
Product Name	(S)-(-)-Indoline-2-Carboxylic Acid Hydrochloride
CAS No.	82923-76-0
Molecular Formula	C9H10ClNO2
Molecular Weight	199.63 g/mol
Synonyms	(S)-Indoline-2-carboxylic acid hydrochloride; (2S)-2,3-Dihydro-1H-indole-2-carboxylic acid hydrochloride; L-Indoline-2-carboxylic acid HCl; (-)-Indoline-2-carboxylic acid hydrochloride; (S)-2-Carboxyindoline hydrochloride; 1,2-Dihydroindole-2-carboxylic acid hydrochloride, (S)-; (S)-2,3-Dihydro-1H-indole-2-carboxylic acid hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-(-)-Indoline-2-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.