Description

Bromoacetyl Chloride, [1-14C] is a carbon-14 labeled derivative of bromoacetyl chloride, a highly reactive bifunctional acylating and alkylating agent. This radiolabeled compound is essential for tracing metabolic pathways and studying reaction mechanisms in pharmaceutical and biochemical research. It is primarily used by researchers and scientists in radiopharmaceutical development, drug metabolism and pharmacokinetics (DMPK) studies, and organic synthesis where isotopic labeling is required for detection and quantification.

Application

• Radiopharmaceutical Precursor: A key building block for synthesizing carbon-14 labeled drug candidates and bioactive molecules for preclinical ADME (Absorption, Distribution, Metabolism, and Excretion) studies.
• Bioconjugation and Protein Labeling: Used to introduce a radioactive tag onto proteins, peptides, or other biomolecules for tracking and imaging applications.
• Metabolic Pathway Tracing: Employed in biochemical research to label specific positions in molecules, enabling detailed investigation of metabolic fate and enzymatic transformations.
• Mechanistic Organic Chemistry Studies: Serves as a tool to elucidate reaction mechanisms in organic synthesis through isotopic labeling.
• Development of Radioligands: Utilized in the synthesis of labeled compounds for receptor binding assays and other diagnostic research tools.
• Chemical Intermediate for Specialty Synthesis: Acts as a reactive intermediate for introducing the bromoacetyl group in complex, isotope-labeled synthetic routes.

Basic Information

Product Name	Bromoacetyl Chloride, [1-14C]
CAS No.	82896-34-2
Molecular Formula	C2H2BrClO * ([1-14C])
Molecular Weight	Contact for details
Synonyms	2-Bromoacetyl Chloride-1-14C; Bromoacetic Acid-1-14C Chloride; [1-14C]-Bromoacetyl Chloride; Carbon-14 Labeled Bromoacetyl Chloride; 2-Bromo-1-chloroethanone-1-14C; α-Bromoacetyl Chloride-1-14C; Bromoacetyl-1-14C Chloride; (1-14C)Bromoacetyl chloride
EINECS	Contact for details

Quality Control

Our radiolabeled compounds are produced and handled under strict quality protocols to ensure high chemical and radiochemical purity, specific activity, and stability. Each batch is analyzed via techniques such as HPLC and radio-HPLC. A comprehensive Certificate of Analysis (COA) detailing chemical purity, radiochemical purity, specific activity, and solvent content is provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at or below -20°C in a dedicated, well-ventilated area for radioactive materials. This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere to maintain stability. Follow all local and international regulations for the storage and handling of radioactive substances.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR / NMR)	Conforms to structure
Chemical Purity (HPLC)	≥ 98%
Radiochemical Purity (Radio-HPLC)	≥ 97%
Specific Activity	Contact for details (mCi/mmol)
Solvent (by 1H NMR / GC)	Specified on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.