Description

Ethyl L-Octahydroindole-2-Carboxylate Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant commercial importance. Its value lies in its role as a key synthon for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. This compound is essential for research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors seeking reliable, high-quality intermediates for synthesis.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptidomimetics Research: Used in medicinal chemistry to develop novel peptide-like compounds with enhanced stability and bioavailability.
• Asymmetric Synthesis: Serves as a valuable precursor in catalytic and stoichiometric asymmetric reactions to introduce stereochemical complexity.
• Agrochemical Development: Employed in the research and production of advanced, chiral agrochemicals and plant protection agents.
• Fine Chemical Production: Utilized in custom synthesis and the manufacture of specialty chemicals for various high-value applications.
• Academic & Industrial R&D: A key reagent for exploring new synthetic methodologies and developing novel chemical entities in laboratory settings.

Basic Information

Product Name	Ethyl L-Octahydroindole-2-Carboxylate Hydrochloride
CAS No.	82864-25-3
Molecular Formula	C11H20ClNO2
Molecular Weight	233.74 g/mol
Synonyms	L-Octahydroindole-2-carboxylic acid ethyl ester hydrochloride; Ethyl (2S)-octahydro-1H-indole-2-carboxylate hydrochloride; (2S)-1,2,3,3a,4,5,6,7-Octahydroindole-2-carboxylic acid ethyl ester hydrochloride; Ethyl L-2-carboxyhexahydroindole hydrochloride; Proline-derived bicyclic ester hydrochloride; (S)-Ethyl octahydroindole-2-carboxylate HCl
EINECS	Contact for details

Quality Control

Our Ethyl L-Octahydroindole-2-Carboxylate Hydrochloride is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.