Description

5-Nitro-1(2H)-Isoquinolinone is a specialized nitro-substituted heterocyclic compound that serves as a versatile and high-value synthetic intermediate. Its core value lies in its unique molecular structure, which makes it a critical building block for constructing more complex molecules in advanced research and development. This product is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic compounds with potential biological activity for drug discovery programs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its nitro and isoquinolinone functionalities.
• Material Science: Serves as a building block for organic electronic materials, dyes, and pigments due to its electron-accepting nitro group.
• Chemical Synthesis: Employed in academic and industrial research as a model substrate for studying nitration reactions and heterocyclic chemistry.
• Ligand & Catalyst Development: The isoquinolinone core can be functionalized to create novel ligands for metal catalysis.

Basic Information

Product Name	5-Nitro-1(2H)-Isoquinolinone
CAS No.	82827-08-5
Molecular Formula	C9H6N2O3
Molecular Weight	190.16 g/mol
Synonyms	5-Nitro-1H-isoquinolin-1-one; 5-Nitroisoquinolin-1(2H)-one; 1(2H)-Isoquinolinone, 5-nitro-; 5-Nitro-1,2-dihydroisoquinolin-1-one; 5-Nitro-1-hydroxyisoquinoline; 5-Nitroisoquinolin-1-ol; 82827-08-5
EINECS	Contact for details

Quality Control

Our 5-Nitro-1(2H)-Isoquinolinone is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). As a strong oxidizer, keep away from heat, sparks, open flames, and incompatible materials such as reducing agents and combustible substances. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.