Description

7H-Isoquino(2,1-D)(1,4)Benzodiazepin-8-Ium, 9,10-Dihydro-3-Chloro-12,13-Dimethoxy-6-(p-Tolyl)-, Bromide is a high-purity, complex heterocyclic organic salt of significant interest in advanced chemical synthesis. This compound serves as a critical intermediate or reference standard for research and development in pharmaceutical and fine chemical sectors. It is primarily needed by R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), particularly within the benzodiazepine analog space, and for analytical method development.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of novel benzodiazepine-derived therapeutic agents.
• Reference Standard: Used for analytical method development, validation, and quality control (HPLC, LC-MS) in pharmaceutical laboratories.
• Chemical Research: Serves as a sophisticated substrate for studying structure-activity relationships (SAR) and novel organic reaction pathways.
• Process Chemistry: Utilized in scaling up synthetic routes for potential drug candidates during preclinical and early development phases.
• Academic Research: Employed in university and institutional labs for advanced studies in medicinal chemistry and heterocyclic compound synthesis.

Basic Information

Product Name	7H-Isoquino(2,1-D)(1,4)Benzodiazepin-8-Ium, 9,10-Dihydro-3-Chloro-12,13-Dimethoxy-6-(p-Tolyl)-, Bromide
CAS No.	82808-81-9
Molecular Formula	C26H24BrClN2O2
Molecular Weight	511.84 g/mol
Synonyms	9,10-Dihydro-3-chloro-12,13-dimethoxy-6-(4-methylphenyl)-7H-isoquino[2,1-d][1,4]benzodiazepin-8-ium bromide; 6-(p-Tolyl)-9,10-dihydro-3-chloro-12,13-dimethoxy-7H-isoquino[2,1-d][1,4]benzodiazepin-8-ium bromide; 82808-81-9; p-Tolyl-substituted benzodiazepinium bromide; Chlorinated dimethoxy isoquinobenzodiazepinium salt
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict in-process controls to ensure batch-to-batch consistency and high chemical purity. Every lot is fully characterized and tested, with a comprehensive Certificate of Analysis (COA) provided, detailing identity, purity, and impurity profiles via techniques such as HPLC, NMR, and mass spectrometry. We support cGMP-compliant manufacturing for applications requiring the highest standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.