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1,2-Dipalmitoyl-D6-Rac-Glycero-3-Pc CAS NO 82765-17-1


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CAS No.:82765-17-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,2-Dipalmitoyl-D6-Rac-Glycero-3-Pc is a deuterated phospholipid analog, specifically a deuterium-labeled form of dipalmitoylphosphatidylcholine. This compound serves as a critical internal standard and tracer in advanced analytical and metabolic research, enabling precise quantification and tracking. It is primarily required by research institutions, pharmaceutical developers, and analytical laboratories engaged in lipidomics, membrane biophysics, and drug metabolism studies.

Application

  • Quantitative Lipidomics: Used as a stable isotope-labeled internal standard for the accurate mass spectrometry-based quantification of phosphatidylcholines in complex biological samples.
  • Metabolic Tracing Studies: Employed as a deuterium tracer to investigate the biosynthesis, turnover, and metabolic pathways of phospholipids in cell culture and in vivo models.
  • Membrane Biophysics Research: Acts as a component in model membrane systems (e.g., liposomes, bilayers) to study lipid-lipid and lipid-protein interactions using techniques like NMR, where deuterium labeling provides distinct spectroscopic signatures.
  • Pharmaceutical R&D: Facilitates the development and validation of bioanalytical methods for lipid-based drug formulations and their pharmacokinetic profiling.
  • Quality Control Reference: Serves as a high-purity reference material for calibrating analytical instruments and validating methods in contract research organizations (CROs) and quality control labs.

Basic Information

Product Name 1,2-Dipalmitoyl-D6-Rac-Glycero-3-Pc
CAS No. 82765-17-1
Molecular Formula C40D6H74NO8P
Molecular Weight ~734.0 g/mol (deuterated form)
Synonyms 1,2-Dihexadecanoyl-D6-rac-glycero-3-phosphocholine; DPPC-d6; 1,2-Dipalmitoyl-d62-rac-glycero-3-phosphocholine; Deuterated DPPC; Dipalmitoylphosphatidylcholine-d6; (2R)-2,3-Bis(hexadecanoyloxy)propyl (2-trimethylammonioethyl) phosphate (deuterated); L-α-Dipalmitoylphosphatidylcholine-d6; rac-DPPC-d6
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Quality Control

Our deuterated phospholipids are produced and handled under strict quality protocols to ensure high isotopic purity and chemical integrity. Each batch is characterized using advanced analytical techniques including NMR and Mass Spectrometry. A comprehensive Certificate of Analysis (COA) is provided, detailing isotopic enrichment, chemical purity, and identity confirmation. We support research requiring traceable and reliable reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item Specification
Appearance White to off-white solid or waxy solid
Identification (NMR) Conforms to structure
Identification (MS) Conforms to structure
Isotopic Purity (Deuterium Enrichment) ≥ 98 atom % D
Chemical Purity (HPLC) ≥ 95%
Solubility Soluble in chloroform, methanol, ethanol; forms liposomes in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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