Description

3-Isoquinolinecarboxylic Acid, 1,2,3,4-Tetrahydro-, 1,1-Dimethylethyl Ester, Hydrochloride is a high-purity, protected heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in providing a versatile and reactive scaffold for constructing complex nitrogen-containing molecular architectures. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile building block for constructing diverse compound libraries in structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Synthesis: Employed in the development of novel pesticides and herbicides, leveraging its heterocyclic core for biological activity.
• Organic Synthesis Reagent: Acts as a protected carboxylic acid derivative for peptide coupling and other condensation reactions to form more complex amides and esters.
• Chemical Biology Probe Development: Utilized in the creation of molecular probes for studying enzyme function and biological pathways.
• Academic & Institutional Research: A valuable compound for methodological development and exploratory synthesis in university and government laboratories.

Basic Information

Product Name	3-Isoquinolinecarboxylic Acid, 1,2,3,4-Tetrahydro-, 1,1-Dimethylethyl Ester, Hydrochloride
CAS No.	82716-90-3
Molecular Formula	C15H20ClNO2
Molecular Weight	281.78 g/mol
Synonyms	1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid tert-butyl ester hydrochloride; tert-Butyl 1,2,3,4-tetrahydroisoquinoline-3-carboxylate hydrochloride; 3-(tert-Butoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride; 1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid tert-butyl ester HCl; Boc-Tic-OH.HCl; Boc-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid hydrochloride; tert-Butyl 3,4-dihydro-1H-isoquinoline-3-carboxylate hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Isoquinolinecarboxylic Acid, 1,2,3,4-Tetrahydro-, 1,1-Dimethylethyl Ester, Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable performance in your sensitive synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.