Description

1,2,3,4-Tetrahydro-6,7-Dimethoxy-3-Isoquinolinecarboxylic Acid Hydrochloride is a high-purity organic salt derivative of a tetrahydroisoquinoline carboxylic acid, serving as a critical advanced pharmaceutical intermediate. Its value lies in providing a reliable, high-quality building block for complex synthetic routes, ensuring downstream product integrity and process consistency. This compound is essential for research chemists and manufacturers in the pharmaceutical and fine chemical industries, particularly those developing new active pharmaceutical ingredients (APIs) and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug discovery.
• Organic Synthesis Building Block: Used for constructing complex heterocyclic frameworks and introducing the tetrahydroisoquinoline moiety into target molecules.
• Biochemical Research: Employed in academic and industrial laboratories as a standard or reagent for studying enzyme interactions, receptor binding, and metabolic pathways.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals, agrochemicals, and other high-value organic compounds requiring precise structural control.

Basic Information

Product Name	1,2,3,4-Tetrahydro-6,7-Dimethoxy-3-Isoquinolinecarboxylic Acid Hydrochloride
CAS No.	82586-62-7
Molecular Formula	C₁₂H₁₅NO₄·HCl
Molecular Weight	273.71 g/mol (Free base: 237.25 g/mol)
Synonyms	6,7-Dimethoxy-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid hydrochloride; 3-Carboxy-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride; 1,2,3,4-Tetrahydro-6,7-dimethoxyisoquinoline-3-carboxylic acid HCl; THIQ-3-COOH hydrochloride; 6,7-Dimethoxytetrahydroisoquinoline-3-carboxylic acid hydrochloride; NSC 339587 hydrochloride; DTXCID10692223
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydro-6,7-Dimethoxy-3-Isoquinolinecarboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.