Description

2-Chlorophenyl(4-Methoxyphenyl) Phosphoramidochloridate is a specialized organophosphorus compound that serves as a critical intermediate in advanced chemical synthesis. Its unique structure, featuring both chlorophenyl and methoxyphenyl groups attached to a reactive phosphoramidochloridate core, makes it a valuable building block for creating complex molecules with tailored properties. This compound is primarily sought by research and development chemists and process engineers in the agrochemical and pharmaceutical industries for the synthesis of novel active ingredients and functional materials.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of novel insecticides, herbicides, and fungicides, particularly those targeting specific enzyme pathways.
• Pharmaceutical Research: Used in medicinal chemistry for the development of potential drug candidates, especially in creating phosphate or phosphoramidate prodrugs and enzyme inhibitors.
• Ligand and Catalyst Synthesis: Serves as a starting material for synthesizing specialized phosphoramidate ligands used in asymmetric catalysis and metal complexation.
• Polymer Modification: Employed to introduce phosphoramidate functional groups into polymer chains, altering material properties like flame retardancy or biocompatibility.
• Chemical Biology Probes: Utilized in the creation of activity-based probes for studying phosphatase and related enzyme families.

Basic Information

Product Name	2-Chlorophenyl(4-Methoxyphenyl) Phosphoramidochloridate
CAS No.	82556-11-4
Molecular Formula	C13H12Cl2NO3P
Molecular Weight	332.11 g/mol
Synonyms	Phosphoramidic chloride, (2-chlorophenyl)(4-methoxyphenyl)-; (2-Chlorophenyl)(4-methoxyphenyl)phosphoramidochloridate; O-(2-Chlorophenyl)-O'-(4-methoxyphenyl) phosphoramidochloridate; Phosphoramidochloridic acid, (2-chlorophenyl)(4-methoxyphenyl) ester; 82556-11-4; 2-Chloro-4'-methoxy-phenylphosphoramidochloridate
EINECS	Contact for details

Quality Control

Every batch of 2-Chlorophenyl(4-Methoxyphenyl) Phosphoramidochloridate is manufactured and tested under a strict quality management system. We ensure product integrity through comprehensive analytical techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity, purity, and the absence of critical impurities. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.