Description

p-Phenetidine-D5 is a deuterium-labeled isotopologue of p-phenetidine, a key aniline derivative. This stable isotope-labeled compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring analytical accuracy and precision. It is primarily required by researchers and quality control laboratories in the pharmaceutical, agrochemical, and forensic toxicology sectors for method development, pharmacokinetic studies, and metabolite identification.

Application

• Internal Standard for LC-MS/MS: Critical for the accurate quantification of p-phenetidine and its metabolites in complex biological matrices like plasma, urine, and tissue homogenates.
• Pharmaceutical Research: Used in drug metabolism and pharmacokinetics (DMPK) studies to track the absorption, distribution, metabolism, and excretion (ADME) of parent compounds.
• Forensic and Clinical Toxicology: Enables precise measurement of exposure to aniline-based compounds in diagnostic and legal contexts.
• Metabolite Identification: Aids in distinguishing drug-derived metabolites from endogenous compounds in mass spectrometric analysis.
• Method Development and Validation: Serves as a reliable reference standard for establishing and calibrating sensitive analytical methods.
• Chemical Synthesis Research: Used as a labeled starting material or intermediate in the synthesis of deuterated complex molecules for mechanistic studies.

Basic Information

Product Name	p-Phenetidine-D5
CAS No.	82460-15-9
Molecular Formula	C8D5H6NO
Molecular Weight	141.20 g/mol
Synonyms	4-Ethoxy-D5-aniline; 4-Aminophenetole-D5; p-Aminophenetole-D5; 1-Amino-4-ethoxybenzene-D5; 4-Ethoxyaniline-D5; Deuterated p-Phenetidine; [D5]-p-Phenetidine; 4-(Ethoxy-d5)aniline
EINECS	Contact for details

Quality Control

Our p-Phenetidine-D5 is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for analytical applications. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR, HPLC, and mass spectrometry, to confirm identity, isotopic enrichment (typically ≥98 atom % D), and chemical purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity	≥98 atom % D
Chemical Purity	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.