Description

1-Methyl-4-(3-Piperidinyl)-1H-Indole Monohydrochloride is a high-purity, heterocyclic organic compound supplied as a hydrochloride salt for enhanced stability and handling. This specialized intermediate is critical for pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up synthetic routes for Active Pharmaceutical Ingredients (APIs).
• Reference Standard: Employed as an analytical standard for method development, validation, and quality control in API manufacturing.
• Biochemical Research: Utilized in the study of biological pathways and receptor-ligand interactions due to its specific indole-piperidine structure.

Basic Information

Product Name	1-Methyl-4-(3-Piperidinyl)-1H-Indole Monohydrochloride
CAS No.	82439-10-9
Molecular Formula	C14H18N2•HCl
Molecular Weight	250.77 g/mol
Synonyms	4-(3-Piperidinyl)-1-methyl-1H-indole hydrochloride; 1-Methyl-4-(piperidin-3-yl)-1H-indole hydrochloride; 1-Methyl-4-(3-piperidyl)indole hydrochloride; 1-Methyl-4-(3-piperidinyl)indole HCl; 4-(3-Piperidyl)-1-methylindole hydrochloride; 82439-10-9; 1H-Indole, 1-methyl-4-(3-piperidinyl)-, monohydrochloride
EINECS	Contact for details

Quality Control

Our 1-Methyl-4-(3-Piperidinyl)-1H-Indole Monohydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.