Description

Glycerol-2-13C is a stable isotope-labeled analog of glycerol, where the carbon atom at the 2-position is enriched with the 13C isotope. This precise labeling is critical for advanced analytical and research applications, providing a non-radioactive tracer for metabolic pathway studies and quantitative analysis. It is an essential tool for researchers and quality control laboratories in the pharmaceutical, biotechnology, and life science sectors requiring high-fidelity isotopic standards.

Application

• Metabolic Flux Analysis (MFA): Used as a 13C-labeled tracer to study and quantify intracellular metabolic pathways in biological systems.
• Drug Metabolism and Pharmacokinetics (DMPK): Serves as an internal standard in LC-MS and GC-MS for the accurate quantification of glycerol and its metabolites in biological fluids.
• NMR Spectroscopy: Provides a distinct 13C NMR signal for structural elucidation and mechanistic studies in organic chemistry and biochemistry.
• Biomedical Research: Enables detailed investigation of lipid metabolism, gluconeogenesis, and energy homeostasis in cell cultures and animal models.
• Quality Control & Reference Standard: Acts as a certified reference material (CRM) for calibrating analytical instruments and validating methods in regulatory environments.
• Stable Isotope Labeling in Cell Culture (SILAC): Can be incorporated into advanced proteomic studies to track protein synthesis and turnover.

Basic Information

Product Name	Glycerol-2-13C
CAS No.	82425-96-5
Molecular Formula	C3H8O3 (with 13C at position 2)
Molecular Weight	93.10 g/mol (13C-labeled)
Synonyms	1,2,3-Propanetriol-2-13C; Glycerin-2-13C; [2-13C]Glycerol; 13C Labeled Glycerol; Glycerol (2-13C); Glycyl alcohol-2-13C; 1,2,3-Trihydroxypropane-2-13C; Isotopic Glycerol
EINECS	Contact for details

Quality Control

Every batch of Glycerol-2-13C is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical data to ensure product integrity, including confirmation of isotopic enrichment (typically ≥99 atom % 13C) and chemical purity via NMR, MS, and HPLC. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting all critical parameters for traceability and compliance with research and regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere to maintain isotopic and chemical purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (NMR)	Conforms to structure
Isotopic Enrichment (atom % 13C)	≥ 99%
Chemical Purity (HPLC)	≥ 98%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.