Description

5-Thiazolecarbonitrile, 2-Chloro-4-Methyl- is a versatile and high-value heterocyclic building block with the CAS registry number 82301-29-9. This compound is critical for the synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing novel thiazole-based scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in antiviral, anticancer, and anti-inflammatory research pipelines.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole moiety.
• Material Science Research: Serves as a precursor for functionalized heterocycles used in organic electronics, ligands for catalysis, and advanced polymers.
• Chemical Biology & Proteomics: Employed as a reactive handle or linker in the synthesis of probes and inhibitors for studying biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	5-Thiazolecarbonitrile, 2-Chloro-4-Methyl-
CAS No.	82301-29-9
Molecular Formula	C5H3ClN2S
Molecular Weight	158.61 g/mol
Synonyms	2-Chloro-4-methylthiazole-5-carbonitrile; 2-Chloro-4-methyl-5-cyanothiazole; 5-Cyano-2-chloro-4-methylthiazole; 2-Chloro-4-methyl-1,3-thiazole-5-carbonitrile; 82301-29-9; 2-Chloro-4-methyl-thiazole-5-carbonitrile; 4-Methyl-2-chloro-5-thiazolecarbonitrile
EINECS	Contact for details

Quality Control

Every batch of 5-Thiazolecarbonitrile, 2-Chloro-4-Methyl- is produced under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.