Description

4-Pyridinethiol, 3-Bromo- is a halogenated pyridine derivative that serves as a versatile and valuable synthetic intermediate in advanced organic chemistry. Its core value lies in the strategic combination of a bromine substituent and a thiol group on the pyridine ring, enabling precise functionalization and the construction of complex heterocyclic systems. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for developing active ingredients and novel ligands.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in the development of kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis, useful in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers, organic semiconductors, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for modifying biomolecules or creating probes to study biological pathways and protein interactions.
• Cross-Coupling Reactions: The bromine atom makes it a suitable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form biaryl structures.

Basic Information

Product Name	4-Pyridinethiol, 3-Bromo-
CAS No.	82264-72-0
Molecular Formula	C5H4BrNS
Molecular Weight	190.06 g/mol
Synonyms	3-Bromo-4-mercaptopyridine; 3-Bromo-4-pyridinethiol; 4-Mercapto-3-bromopyridine; 3-Bromo-4-pyridyl mercaptan; 3-Bromo-4-thiopyridinol; 4-Pyridinethiol, 3-bromo-; 3-Bromopyridine-4-thiol
EINECS	Contact for details

Quality Control

Our 4-Pyridinethiol, 3-Bromo- is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.