Description

Halofuginone Lactate is a semi-synthetic quinazolinone alkaloid derivative, specifically formulated as the lactate salt to enhance solubility and bioavailability. This compound is valued for its potent antiprotozoal and antifibrotic properties, making it a critical active pharmaceutical ingredient (API) in veterinary and research applications. It is primarily sought by manufacturers in the animal health sector and by research institutions investigating pathways related to collagen synthesis and immune modulation.

Application

• Primary use as an active pharmaceutical ingredient (API) in veterinary coccidiostats for poultry and livestock.
• Key component in medicated feed premixes and water-soluble formulations for disease prevention.
• Research chemical for studying TGF-β signaling pathways and extracellular matrix deposition.
• Investigational agent in preclinical studies for anti-fibrotic therapies targeting liver, lung, and skin disorders.
• Reference standard in analytical laboratories for quality control and method development.
• Intermediate in the synthesis of more complex quinazolinone derivatives for pharmacological screening.

Basic Information

Product Name	Halofuginone Lactate
CAS No.	82186-71-8
Molecular Formula	C₁₆H₁₇BrClN₃O₃ • C₃H₆O₃
Molecular Weight	495.71 g/mol (for the lactate salt)
Synonyms	Halofuginone Hydrobromide Lactate; 7-Bromo-6-chloro-3-[3-(3-hydroxy-2-piperidinyl)-2-oxopropyl]-4(3H)-quinazolinone lactate; Stenorol (trade name); RU-19110; Febrifugine derivative; (+)-Halofuginone Lactate; Trans-Halofuginone Lactate
EINECS	Contact for details

Quality Control

Our Halofuginone Lactate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for assay and related substances, residual solvent analysis, and identification by IR and MS. We provide full traceability and Certificates of Analysis (COA) that detail compliance with agreed specifications, supporting your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.