Description

Dichloroacetic Acid-Od is a specialized, isotopically labeled derivative of dichloroacetic acid, where the oxygen atom is replaced by the stable isotope oxygen-18 (¹⁸O). This compound is essential for advanced analytical and research applications where precise molecular tracking and quantification are required. It is primarily utilized by researchers and scientists in pharmaceutical development, metabolic studies, and environmental analysis who require high-purity, isotopically labeled standards for mass spectrometry and tracer experiments.

Application

• As an internal standard in quantitative mass spectrometry (LC-MS, GC-MS) for the accurate measurement of dichloroacetic acid and related metabolites.
• Use in metabolic pathway tracing and pharmacokinetic studies to investigate the fate and distribution of dichloroacetic acid in biological systems.
• Employed as a tracer compound in environmental science to study the degradation and transformation of chlorinated acetic acids.
• Critical reagent in the synthesis of isotopically labeled pharmaceutical intermediates for drug discovery and development.
• Used in analytical method development and validation to ensure accuracy, precision, and regulatory compliance.
• Application in fundamental chemical research involving reaction mechanisms where oxygen atom transfer is studied.

Basic Information

Product Name	Dichloroacetic Acid-Od
CAS No.	82093-18-3
Molecular Formula	C₂HCl₂¹⁸O₂H (commonly noted as C₂H₂Cl₂O₂ with ¹⁸O labeling)
Molecular Weight	~130.94 g/mol (varies slightly based on isotopic enrichment)
Synonyms	Dichloroacetic-¹⁸O₂ Acid; [¹⁸O₂]-Dichloroacetic Acid; DCA-¹⁸O₂; 2,2-Dichloroacetic-¹⁸O₂ Acid; Oxygen-18 Labeled Dichloroacetic Acid; Isotopically Labeled Dichloroacetic Acid; DCA-Od; Dichloro(¹⁸O)acetic Acid
EINECS	Contact for details

Quality Control

Every batch of Dichloroacetic Acid-Od is produced and analyzed under stringent conditions to ensure exceptional isotopic and chemical purity, critical for sensitive research applications. We provide comprehensive Certificates of Analysis (COA) detailing isotopic enrichment (atom % ¹⁸O), chemical purity by HPLC, and identity confirmation by spectroscopic methods. Our quality system is designed to meet the rigorous demands of analytical and pharmaceutical reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and properties as a strong acid/organic solvent, the container must be kept tightly sealed to prevent moisture absorption and degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR/NMR)	Conforms to structure
Isotopic Enrichment (Atom % ¹⁸O)	≥95% (Typical 97-99%)
Chemical Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Chloride Content	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.