Description

3-Phenyl-2-(Thiophene-2-Sulfonylamino)-Propionic Acid is a high-purity, non-natural amino acid derivative featuring a unique thiophene sulfonamide moiety. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly protease inhibitors and enzyme modulators.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel pesticides and herbicides.
• Peptidomimetic Synthesis: Employed in the design and construction of peptide analogs with enhanced stability and bioavailability.
• Chemical Biology Probes: Utilized to create labeled compounds or affinity probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A starting material for the custom production of complex, target-specific molecules for clients.

Basic Information

Item	Detail
Product Name	3-Phenyl-2-(Thiophene-2-Sulfonylamino)-Propionic Acid
CAS No.	82068-16-4
Molecular Formula	C13H13NO4S2
Molecular Weight	311.38 g/mol
Synonyms	2-[(Thiophen-2-ylsulfonyl)amino]-3-phenylpropanoic acid; 3-Phenyl-2-[(thiophene-2-sulfonyl)amino]propionic acid; 2-(Thiophene-2-sulfonylamino)-3-phenylpropionic acid; N-(Thiophene-2-sulfonyl)-3-phenylalanine; 3-Phenyl-2-(2-thienylsulfonylamino)propanoic acid; 82068-16-4; 3-Phenyl-2-(thiophene-2-sulfonamido)propanoic acid
EINECS	Contact for details

Quality Control

Our 3-Phenyl-2-(Thiophene-2-Sulfonylamino)-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.