Description

2-Amino-3-(trideuteromethyl)-3H-imidazo[4,5-f]-quinoline is a deuterated derivative of the heterocyclic aromatic amine 2-amino-3-methylimidazo[4,5-f]quinoline (IQ), a compound of significant research interest. This deuterated analog is a critical tool for advanced analytical and metabolic studies, providing enhanced detection and tracing capabilities. It is primarily utilized by research institutions and pharmaceutical companies engaged in toxicology, carcinogenesis research, and the development of analytical reference standards.

Application

• Metabolic Pathway Tracing: Acts as a stable isotope-labeled internal standard in mass spectrometry for quantifying IQ and its metabolites in complex biological matrices.
• Toxicology & Carcinogenesis Research: Used in studies investigating the formation, distribution, and biological effects of heterocyclic aromatic amines (HAAs) from cooked foods.
• Analytical Reference Standard: Serves as a high-purity certified reference material (CRM) for method development and validation in food safety and environmental analysis.
• Pharmacokinetic Studies: Enables precise tracking of absorption, distribution, metabolism, and excretion (ADME) profiles in preclinical research.
• DNA Adduct Research: Facilitates the study of DNA damage mechanisms by allowing sensitive detection of specific adducts formed by this class of compounds.

Basic Information

Product Name	2-Amino-3-(trideuteromethyl)-3H-imidazo[4,5-f]-quinoline
CAS No.	82050-10-0
Molecular Formula	C11H8D3N5
Molecular Weight	214.24 g/mol
Synonyms	2-Amino-3-(trideuteromethyl)imidazo[4,5-f]quinoline; Deuterated IQ; IQ-d3; 2-Amino-3-(methyl-d3)imidazo[4,5-f]quinoline; 3-(Trideuteromethyl)-3H-imidazo[4,5-f]quinolin-2-amine; 2-Amino-3-(CD3)-IQ; 2-Amino-3-(methyl-D3)-3H-imidazo[4,5-f]quinoline; 82050-10-0
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced under strict quality control to ensure high isotopic purity and chemical integrity, essential for reliable research data. Each batch is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing chemical purity, isotopic enrichment (D%), and chromatographic data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at -20°C under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystals
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Isotopic Purity (D%)	≥ 98 atom % D
Water Content (KF)	≤ 1.0 %
Residue on Ignition	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.