Description

12-Mercaptododecanoic Acid is a high-purity, long-chain thiol fatty acid derivative that serves as a critical functional intermediate. Its unique bifunctional structure, featuring both a terminal thiol (-SH) and a carboxylic acid (-COOH) group, enables versatile chemical modifications and surface functionalization. This compound is essential for researchers and manufacturers in the pharmaceutical, nanotechnology, and advanced materials sectors, where precise molecular assembly and controlled surface chemistry are paramount.

Application

• Self-Assembled Monolayer (SAM) Formation: A key precursor for creating highly ordered, functional monolayers on gold, silver, and other metal surfaces for sensors, corrosion inhibition, and surface patterning.
• Nanoparticle Capping & Stabilization: Used to functionalize and stabilize quantum dots, gold nanoparticles, and other nanomaterials, providing colloidal stability and enabling further bioconjugation.
• Polymer Modification & Crosslinking: Acts as a chain transfer agent (CTA) in controlled radical polymerizations (e.g., RAFT) and as a crosslinker or functional modifier for polymers and resins.
• Bioconjugation & Ligand Synthesis: The carboxylic acid group allows for easy coupling to biomolecules (peptides, proteins) or other ligands, creating thiolated probes for diagnostics and targeted delivery systems.
• Lubricant & Fuel Additive Intermediate: Serves as a building block for synthesizing extreme pressure (EP) additives and multifunctional antioxidants for advanced lubricant formulations.
• Surface-Enhanced Raman Scattering (SERS) Substrates: Used to create reproducible and sensitive SERS-active surfaces for analytical chemistry and biosensing applications.

Basic Information

Product Name	12-Mercaptododecanoic Acid
CAS No.	82001-53-4
Molecular Formula	C12H24O2S
Molecular Weight	232.38 g/mol
Synonyms	12-Mercaptolauric Acid; Dodecanoic acid, 12-mercapto-; 12-Sulfanyldodecanoic acid; 12-Thiododecanoic acid; ω-Mercaptododecanoic acid; 12-Mercapto-dodecansäure (German); Acide 12-mercaptododécanoïque (French); Lauric acid, 12-mercapto-
EINECS	Contact for details

Quality Control

Our 12-Mercaptododecanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation of the thiol group and ensure long-term stability. Keep the container in a cool, dry, and well-ventilated area, separate from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	78 - 82 °C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.