Description

[12As,(+)]-1,2,3,12Aβ-Tetrahydro-1-Methyl-6,8,9-Trimethoxy-12H-[1]Benzoxepino[2,3,4-Ij]Isoquinoline is a complex, chiral isoquinoline alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. Its intricate fused-ring structure makes it a valuable intermediate or reference standard for developing novel bioactive compounds. This high-purity chemical is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the discovery of new therapeutic agents.

Application

• Pharmaceutical Research & Development: Serves as a key chiral building block or pharmacophore model in the synthesis of potential new drug candidates targeting neurological or other disorders.
• Reference Standard for Analytical Chemistry: Used as a high-purity standard for method development, validation, and quality control in HPLC, LC-MS, or NMR analysis within analytical laboratories.
• Academic & Process Chemistry: Employed in university and industrial labs to study complex organic reactions, asymmetric synthesis, and the properties of benzoxepino-isoquinoline frameworks.
• Biochemical Research: Investigated for its potential biological activity and interaction with various enzymes or receptors in biochemical assays.
• Fine Chemical Synthesis: Acts as a specialized intermediate for the custom synthesis of more complex molecules for clients in the life sciences sector.

Basic Information

Product Name	[12As,(+)]-1,2,3,12Aβ-Tetrahydro-1-Methyl-6,8,9-Trimethoxy-12H-[1]Benzoxepino[2,3,4-Ij]Isoquinoline
CAS No.	81874-23-9
Molecular Formula	C22H25NO5
Molecular Weight	383.44 g/mol
Synonyms	(+)-[12As]-1,2,3,12aβ-Tetrahydro-1-methyl-6,8,9-trimethoxy-12H-[1]benzoxepino[2,3,4-ij]isoquinoline; (12As)-1,2,3,12a-Tetrahydro-1-methyl-6,8,9-trimethoxy-12H-[1]benzoxepino[2,3,4-ij]isoquinoline; NSC 339587; Benzoxepino[2,3,4-ij]isoquinoline derivative; (+)-Isomer of the benzoxepino-isoquinoline alkaloid. Contact for additional trade names or abbreviations.
EINECS	Contact for details

Quality Control

Our [12As,(+)]-1,2,3,12Aβ-Tetrahydro-1-Methyl-6,8,9-Trimethoxy-12H-[1]Benzoxepino[2,3,4-Ij]Isoquinoline is produced and handled under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and spectroscopic identification (NMR, IR, MS), to ensure it meets exacting specifications for research use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light). For long-term storage, consider storing under inert atmosphere at lower temperatures (e.g., 2-8°C) to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.