Description

2-(7-Chloro-1H-Indol-3-Yl)-Ethylamine Hydrochloride is a high-purity, pharmaceutically relevant indole derivative, serving as a critical building block in modern organic synthesis. Its value lies in providing a versatile and functionalized scaffold for the development of novel bioactive compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those focused on central nervous system (CNS) agents, serotonin receptor modulators, and other therapeutic small molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting neurological and psychiatric disorders.
• Serotonergic Compound Research: Used in the development and study of ligands for serotonin (5-HT) receptor subtypes due to its indole-ethylamine core structure.
• Medicinal Chemistry: Serves as a versatile building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Research: Employed as a standard or reference compound in analytical and pharmacological research laboratories.
• Fine Chemical Synthesis: Utilized in multi-step synthetic routes to create complex, high-value specialty chemicals.

Basic Information

Product Name	2-(7-Chloro-1H-Indol-3-Yl)-Ethylamine Hydrochloride
CAS No.	81868-13-5
Molecular Formula	C10H12Cl2N2
Molecular Weight	231.12 g/mol
Synonyms	7-Chlorotryptamine Hydrochloride; 2-(7-Chloro-1H-indol-3-yl)ethan-1-amine Hydrochloride; 7-Chloro-3-(2-aminoethyl)indole Hydrochloride; 7-Chloro-1H-indole-3-ethanamine Hydrochloride; 7-Chloro-3-(2-aminoethyl)-1H-indole Hydrochloride; 7-Chlorotryptamine HCl; 7-Cl-Tryptamine HCl
EINECS	Contact for details

Quality Control

Our 2-(7-Chloro-1H-Indol-3-Yl)-Ethylamine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.