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(2-Acetoxyethoxy)-Methyl Bromide CAS NO 81777-40-4


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CAS No.:81777-40-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(2-Acetoxyethoxy)-Methyl Bromide is a specialized bromomethyl ether derivative, a versatile bifunctional alkylating agent and a key synthetic intermediate in organic chemistry. Its molecular structure, featuring both a reactive bromomethyl group and a protected acetoxyethoxy side chain, makes it a valuable building block for the controlled introduction of functionalized ethylene glycol linkers. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries who require high-purity intermediates for constructing complex molecules, such as prodrugs, polymer precursors, and advanced materials.

Application

  • Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing prodrug linkers and targeted drug delivery systems.
  • Polymer Chemistry: Serves as a functional monomer or cross-linking agent for synthesizing specialty polymers with tailored properties, including hydrogels and functionalized polyethylene glycol (PEG) derivatives.
  • Ligand and Conjugate Synthesis: Used to attach polyethylene glycol (PEG) chains or other functional groups to biomolecules, peptides, or small molecules, enhancing solubility or targeting.
  • Material Science: Intermediate in the production of surface-modifying agents and advanced materials requiring specific ether-linked functionalities.
  • Organic Synthesis: A versatile alkylating agent for introducing the (2-acetoxyethoxy)methyl moiety into various molecular scaffolds under controlled conditions.
  • Agrochemical Research: Potential intermediate in the development of novel herbicides or plant growth regulators that utilize ether-based functional groups.

Basic Information

Product Name (2-Acetoxyethoxy)-Methyl Bromide
CAS No. 81777-40-4
Molecular Formula C6H11BrO3
Molecular Weight 211.06 g/mol
Synonyms Bromomethyl 2-acetoxyethyl ether; 2-(Bromomethoxy)ethyl acetate; 1-Acetoxy-2-(bromomethoxy)ethane; (Acetoxyethoxy)methyl bromide; 2-(Bromomethoxy)ethyl ethanoate; [(2-Acetoxyethoxy)methyl]bromide; Bromo(2-acetoxyethoxymethane)
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Quality Control

Our (2-Acetoxyethoxy)-Methyl Bromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including assay (HPLC), identity confirmation (IR, NMR), and impurity profiling, to ensure it meets the high-purity standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature and reactive bromide group, prolonged exposure to light, heat, or moisture should be avoided to maintain product integrity.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Related Substances (HPLC) Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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