Description

Bambuterol Monocarbamate is a key pharmaceutical intermediate and prodrug of the β-2 adrenergic agonist, bambuterol. Its primary value lies in its role as a precursor in the synthesis of active pharmaceutical ingredients (APIs) used in respiratory therapeutics. This compound is essential for manufacturers in the pharmaceutical industry, particularly those developing and producing long-acting bronchodilators for the management of conditions such as asthma and chronic obstructive pulmonary disease (COPD).

Application

• Pharmaceutical Intermediate: Primary use as a critical precursor in the synthesis of the active pharmaceutical ingredient (API) Bambuterol Hydrochloride.
• Respiratory Drug Manufacturing: Integral to the production of long-acting bronchodilator medications for asthma and chronic obstructive pulmonary disease (COPD).
• Prodrug Development: Serves as a model compound in research focused on prodrug strategies to enhance drug bioavailability and duration of action.
• Analytical Reference Standard: Used as a high-purity standard in quality control (QC) and research & development (R&D) laboratories for method development and validation.
• Clinical Research Material: Supplied as a raw material for non-clinical and clinical studies investigating new respiratory formulations.

Basic Information

Item	Details
Product Name	Bambuterol Monocarbamate
CAS No.	81732-52-7
Molecular Formula	C18H29N3O5
Molecular Weight	367.44 g/mol
Synonyms	Bambuterol Carbamate; 5-[2-[(1,1-Dimethylethyl)amino]-1-hydroxyethyl]-1,3-phenylene bis(dimethylcarbamate); KWD 2183; Terbutaline bisdimethylcarbamate; Bambec precursor; 1,3-Phenylene bis(dimethylcarbamate) derivative of terbutaline
EINECS	Contact for details

Quality Control

Our Bambuterol Monocarbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via techniques such as HPLC, IR, and NMR, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) documenting full compliance with agreed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, the container should be stored in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.