Description

Norvaline-4,4-T2, 5-(Methylthio)- (9Ci) is a specialized, isotopically labeled derivative of the non-proteinogenic amino acid norvaline, incorporating deuterium (T2) and a methylthio functional group. This compound is of significant value in advanced research and development, particularly for its role as a stable isotope-labeled internal standard or a biochemical tracer. It is primarily sought by scientists and process developers in the pharmaceutical, agrochemical, and life science research sectors for applications in metabolic studies, pharmacokinetics, and analytical method development.

Application

• Metabolic Pathway Tracing: Used as a deuterium-labeled tracer in biochemical and pharmacological research to study amino acid metabolism and drug disposition.
• Mass Spectrometry Internal Standard: Serves as a critical, isotopically labeled internal standard for the precise quantification of norvaline analogs or related metabolites via LC-MS/MS and GC-MS.
• Pharmaceutical Intermediate: Acts as a building block in the synthesis of more complex, sulfur-containing peptide mimetics or novel therapeutic candidates.
• Enzyme Substrate Studies: Employed in enzymatic assays to investigate the activity and inhibition of enzymes that process sulfur-containing amino acids or their derivatives.
• Agrochemical Research: Utilized in the development and study of novel amino acid-based herbicides or plant growth regulators.
• Nutritional Science Research: Applied in studies investigating the role of modified amino acids in specialized diets or metabolic conditions.

Basic Information

Product Name	Norvaline-4,4-T2, 5-(Methylthio)- (9Ci)
CAS No.	81625-00-5
Molecular Formula	C6H11D2NO2S
Molecular Weight	165.24 g/mol (for deuterated form)
Synonyms	5-(Methylthio)-2-amino-norvaline-4,4-d2; 2-Amino-5-(methylthio)pentanoic acid-4,4-d2; L-Norvaline, 5-(methylthio)-, 4,4-d2; (S)-2-Amino-5-(methylthio)pentanoic-4,4-d2 acid; Deuterated 5-Methylthionorvaline; 4,4-Dideutero-5-(methylthio)-L-norvaline; 5-MT-Nva-d2
EINECS	Contact for details

Quality Control

Our production of this high-value biochemical is supported by rigorous quality testing to ensure batch-to-batch consistency and isotopic purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and specific identity tests is provided with every shipment to support your research integrity and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Enrichment (MS)	≥ 98 atom % D
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.