Description

4-(5-Bromo-Thiophene-2-Sulfonyl)-Morpholine is a high-value sulfonamide-based organic intermediate with a distinct brominated thiophene core. This compound is critical for its role as a versatile building block in advanced pharmaceutical and agrochemical synthesis, enabling the introduction of specific functional groups. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and other small molecule therapeutic research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiophene-sulfonamide moiety.
• Material Science Research: Serves as a precursor for functionalized polymers or organic electronic materials due to its conjugated thiophene system.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Product Name	4-(5-Bromo-Thiophene-2-Sulfonyl)-Morpholine
CAS No.	81597-64-0
Molecular Formula	C9H10BrNO3S2
Molecular Weight	324.22 g/mol
Synonyms	Morpholine, 4-[(5-bromo-2-thienyl)sulfonyl]-; 4-(5-Bromothiophene-2-sulfonyl)morpholine; 5-Bromo-2-morpholinosulfonylthiophene; 2-Thiophenesulfonamide, N-(5-bromo-2-thienyl)-, N-morpholino derivative; 81597-64-0; 4-(5-Bromo-2-thienylsulfonyl)morpholine; 4-[(5-Bromothiophen-2-yl)sulfonyl]morpholine
EINECS	Contact for details

Quality Control

Our 4-(5-Bromo-Thiophene-2-Sulfonyl)-Morpholine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding R&D and scale-up processes. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is supplied with each batch to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.