Description

5-Bromo-Thiophene-2-Sulfonic Acid Isopropylamide is a specialized sulfonamide derivative of brominated thiophene, serving as a high-value synthetic intermediate. Its core value lies in its unique molecular structure, which provides a reactive handle for further functionalization, making it essential for constructing complex heterocyclic systems. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the thiophene scaffold for bioactivity.
• Material Science: Serves as a precursor for functional polymers, conductive materials, and organic semiconductors due to the electron-rich thiophene core.
• Chemical Synthesis: Acts as a versatile reagent for introducing the 5-bromo-thiophene-2-sulfonyl moiety into larger molecules via coupling or substitution reactions.
• Ligand & Catalyst Development: Utilized in creating novel ligands for metal catalysis and organocatalysts for asymmetric synthesis.

Basic Information

Product Name	5-Bromo-Thiophene-2-Sulfonic Acid Isopropylamide
CAS No.	81597-54-8
Molecular Formula	C7H10BrNO2S2
Molecular Weight	284.19 g/mol
Synonyms	5-Bromo-2-thiophenesulfonamide, N-(1-methylethyl)-; N-Isopropyl-5-bromothiophene-2-sulfonamide; 5-Bromothiophene-2-sulfonic acid isopropylamide; 2-Thiophenesulfonamide, 5-bromo-N-(1-methylethyl)-; Isopropyl 5-bromothiophene-2-sulfonamide; 81597-54-8; 5-Bromo-N-isopropylthiophene-2-sulfonamide
EINECS	Contact for details

Quality Control

Our 5-Bromo-Thiophene-2-Sulfonic Acid Isopropylamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.