Description

Dihomo-γ-Linolenic Acid-D6 is a stable isotope-labeled analog of the ω-6 fatty acid, dihomo-γ-linolenic acid (DGLA), where six hydrogen atoms are replaced by deuterium. This compound is an essential internal standard for the precise quantification of DGLA in complex biological matrices using mass spectrometry. It is primarily required by researchers and quality control laboratories in the pharmaceutical, nutraceutical, and clinical diagnostics sectors for advanced lipidomics studies, metabolic pathway analysis, and the development of accurate biomarker assays.

Application

• Mass Spectrometry Internal Standard: Critical for the accurate quantitative analysis of endogenous DGLA levels in plasma, serum, and tissue samples via GC-MS or LC-MS/MS.
• Biomedical & Lipidomics Research: Used to trace metabolic fluxes in the arachidonic acid biosynthesis pathway and study eicosanoid production in inflammatory and metabolic diseases.
• Pharmaceutical Development: Supports drug discovery and pharmacokinetic studies targeting fatty acid desaturase and elongase enzymes.
• Clinical Diagnostics: Enables the standardization of assays measuring fatty acid profiles for nutritional status assessment and disease biomarker validation.
• Nutraceutical & Dietary Supplement Analysis: Ensures accurate potency testing and quality control of products containing γ-linolenic acid (GLA) and its metabolites.

Basic Information

Product Name	Dihomo-γ-Linolenic Acid-D6
CAS No.	81540-86-5
Molecular Formula	C20H30D6O2
Molecular Weight	314.52 g/mol
Synonyms	8Z,11Z,14Z-Eicosatrienoic-17,17,18,18,19,19-d6 Acid; DGLA-d6; Dihomo-γ-linolenic Acid-d6; (8Z,11Z,14Z)-Icosatrienoic-17,17,18,18,19,19-d6 Acid; 20:3 n-6-d6; 8,11,14-Eicosatrienoic Acid-d6; all-cis-8,11,14-Eicosatrienoic Acid-d6; 20:3ω6-d6
EINECS	Contact for details

Quality Control

Our Dihomo-γ-Linolenic Acid-D6 is manufactured under strict quality systems to ensure the high chemical purity and isotopic enrichment required for analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic purity (atom % D), chemical purity by HPLC, and confirmation of structure. We adhere to relevant standards for high-purity reference materials to ensure reliable and reproducible results in your critical research and testing.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. For long-term storage, solutions should be prepared in appropriate, degassed solvents and kept frozen.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil
Identification (IR / NMR)	Conforms to structure
Purity (HPLC)	≥ 98%
Isotopic Purity	≥ 98 atom % D
Chemical Purity (Assay)	≥ 95%
Solubility	Soluble in ethanol, DMSO, chloroform

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.