Description

Methyl 4-Amino-5-Methylthiophene-3-Carboxylate is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its versatile reactivity, serving as a key precursor for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries for developing new active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic small molecules.
• Agrochemical Synthesis: Used as a key precursor for developing advanced pesticides, herbicides, and fungicides, leveraging the thiophene scaffold for bioactivity.
• Material Science Research: Serves as a monomer or functional unit in the development of organic semiconductors, conductive polymers, and other specialty electronic materials.
• Dye and Pigment Manufacturing: Employed in the synthesis of complex heterocyclic dyes and organic pigments due to its amino and ester functional groups.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including novel ring-forming reactions and catalysis research.
• Custom Synthesis & Scale-Up: Provides a reliable starting point for contract manufacturing organizations (CMOs) and fine chemical suppliers for custom synthesis projects from gram to kilogram scale.

Basic Information

Product Name	Methyl 4-Amino-5-Methylthiophene-3-Carboxylate
CAS No.	81528-48-5
Molecular Formula	C8H11NO2S
Molecular Weight	185.24 g/mol
Synonyms	Methyl 4-Amino-5-Methyl-3-thiophenecarboxylate; 4-Amino-5-methylthiophene-3-carboxylic acid methyl ester; 3-Thiophenecarboxylic acid, 4-amino-5-methyl-, methyl ester; 5-Methyl-4-aminothiophene-3-carboxylic acid methyl ester; Methyl 5-methyl-4-aminothiophene-3-carboxylate; 4-Amino-5-methyl-3-thiophenecarboxylic acid methyl ester; 4-Amino-5-methylthiophene-3-methyl carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 4-Amino-5-Methylthiophene-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Light yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.