Description

2,4-Thiazolidinedione, 5-Chloro- is a halogenated derivative of the thiazolidinedione heterocyclic scaffold, a structure of significant pharmacological interest. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in medicinal chemistry research. It is primarily utilized by pharmaceutical R&D departments and fine chemical synthesis teams for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of thiazolidinedione-based drug candidates, particularly for metabolic disorders.
• Medicinal Chemistry Research: Core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• PPAR Modulator Development: Building block for creating novel peroxisome proliferator-activated receptor (PPAR) agonists and antagonists.
• Chemical Biology Probes: Used to develop tool compounds for studying biological pathways related to diabetes and inflammation.
• Fine Chemical Synthesis: Intermediate for the custom synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	2,4-Thiazolidinedione, 5-Chloro-
CAS No.	81515-94-8
Molecular Formula	C3H2ClNO2S
Molecular Weight	151.57 g/mol
Synonyms	5-Chloro-2,4-thiazolidinedione; 5-Chloro-1,3-thiazolidine-2,4-dione; 5-Chlorothiazolidine-2,4-dione; 5-Chloro-2,4-dioxothiazolidine; Chlorothiazolidinedione; TZD Chloro derivative; 81515-94-8
EINECS	Contact for details

Quality Control

We supply 2,4-Thiazolidinedione, 5-Chloro- in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with internal specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.