Description

n-(Thexyldimethylsilyl)dimethylamine is a specialized organosilicon compound, specifically a silylamine, valued for its role as a versatile silylating agent and synthetic intermediate. Its primary commercial value lies in introducing the bulky, lipophilic thexyldimethylsilyl (TDS) protecting group, which offers unique steric and stability properties compared to more common silyl groups. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise protection of sensitive functional groups during complex synthesis.

Application

• Pharmaceutical Intermediate: Used as a key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for protecting hydroxyl groups during multi-step reactions.
• Agrochemical Synthesis: Employed in the production of advanced pesticides and herbicides where selective silylation is required to control reactivity.
• Polymer & Material Science: Acts as a modifier or cross-linking agent in the development of specialty silicones and silicon-based polymers.
• Organic Synthesis Reagent: A valuable tool in research laboratories for the protection of alcohols, phenols, and carboxylic acids under mild conditions.
• Nucleoside & Carbohydrate Chemistry: Utilized for the selective protection of sugar hydroxyls in the synthesis of nucleoside analogs and complex carbohydrates.
• Production of Silicon-Containing Monomers: Serves as a precursor for creating custom silane monomers used in surface treatments and coatings.

Basic Information

Product Name	n-(Thexyldimethylsilyl)dimethylamine
CAS No.	81484-86-8
Molecular Formula	C11H27NSi
Molecular Weight	201.43 g/mol
Synonyms	Dimethyl(thexyldimethylsilyl)amine; TDS-DMA; Thexyldimethylsilyl dimethylamine; N-(Dimethyl(thexyldimethylsilyl)amine; (Dimethylamino)thexyldimethylsilane; 1,1,2-Trimethylpropyl(dimethyl)(dimethylamino)silane; N-(Thexyldimethylsilyl)-N-methylmethanamine; TDS Protecting Group Reagent
EINECS	Contact for details

Quality Control

Our n-(Thexyldimethylsilyl)dimethylamine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including assay by GC or NMR and impurity profiling. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements or internal standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.