Description

Methyl 3-Methylthiophene-2-Carboxylate is a high-purity organic building block and heterocyclic intermediate of significant commercial importance. This compound is valued for its role as a versatile synthon in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and advanced material sectors for constructing thiophene-based scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) containing the thiophene moiety, which is prevalent in drugs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the thiophene ring contributes to biological activity.
• Material Science Research: Serves as a monomer or building block for creating conjugated polymers and organic electronic materials, such as those used in organic light-emitting diodes (OLEDs) and semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal catalysis and organocatalysts used in asymmetric synthesis.
• Flavor and Fragrance Industry: Acts as an intermediate for the synthesis of certain sulfur-containing aroma compounds.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up processes.

Basic Information

Product Name	Methyl 3-Methylthiophene-2-Carboxylate
CAS No.	81452-54-2
Molecular Formula	C7H8O2S
Molecular Weight	156.20 g/mol
Synonyms	3-Methylthiophene-2-carboxylic acid methyl ester; Methyl 3-methyl-2-thiophenecarboxylate; 2-Thiophenecarboxylic acid, 3-methyl-, methyl ester; 3-Methyl-2-thiophenecarboxylic acid methyl ester; 2-Methoxycarbonyl-3-methylthiophene; 3-Methylthiophene-2-methyl carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 3-Methylthiophene-2-Carboxylate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.