Description

Ethyl 2-Chlorothiazole-5-Carboxylate is a high-purity organic building block and key heterocyclic intermediate essential for advanced chemical synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce functionalized thiazole motifs into their target compounds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and anti-inflammatory agents.
• Agrochemical Synthesis: Serves as a key building block for developing advanced herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Research: Used in the development of organic electronic materials, ligands for catalysis, and novel polymers requiring specific heterocyclic architectures.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs (Contract Development and Manufacturing Organizations) for the scalable production of client-specified target molecules.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new chemical spaces in medicinal chemistry and synthetic organic chemistry programs.

Basic Information

Product Name	Ethyl 2-Chlorothiazole-5-Carboxylate
CAS No.	81449-93-6
Molecular Formula	C6H6ClNO2S
Molecular Weight	191.64 g/mol
Synonyms	Ethyl 2-chloro-1,3-thiazole-5-carboxylate; 2-Chloro-5-(ethoxycarbonyl)thiazole; 5-Carbethoxy-2-chlorothiazole; Ethyl 5-carboxy-2-chlorothiazole; 2-Chlorothiazole-5-carboxylic acid ethyl ester; 81449-93-6; 2-Chloro-thiazole-5-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-Chlorothiazole-5-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.