Description

1H-Pyrazole, 4-Ethoxy- is a functionalized pyrazole derivative, a versatile heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in providing a scaffold for constructing complex molecules with tailored properties, particularly in the development of active pharmaceutical ingredients and specialty agrochemicals. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific ethoxy-substituted pyrazole motifs into their target structures.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Serves as a crucial building block for creating new-generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand and Catalyst Development: Used in the design and synthesis of specialized ligands for metal catalysis and organocatalysts, enabling novel synthetic transformations.
• Material Science Research: Employed as a monomer or functional additive in the development of advanced polymers, dyes, and organic electronic materials.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways due to its ability to mimic biological heterocycles.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	1H-Pyrazole, 4-Ethoxy-
CAS No.	81437-10-7
Molecular Formula	C5H8N2O
Molecular Weight	112.13 g/mol
Synonyms	4-Ethoxypyrazole; 4-Ethoxy-1H-pyrazole; 1H-Pyrazole, 4-ethoxy-; Ethoxypyrazole; Pyrazole, 4-ethoxy-; 4-Ethoxy-pyrazole; 4-Ethoxy-1H-pyrazol
EINECS	Contact for details

Quality Control

Our 1H-Pyrazole, 4-Ethoxy- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive quality assurance, with standard specifications typically meeting or exceeding 98.0% purity (by HPLC). Each batch is accompanied by a detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles. Our quality protocols are designed to support cGMP compliance for pharmaceutical applications, and we can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.