Description

m-Nitrophenyl-D4 Bromide is a deuterated aromatic bromide compound, specifically labeled with four deuterium atoms. This isotopic labeling is critical for applications requiring precise tracking and analysis, offering enhanced stability and distinct spectral properties compared to its non-deuterated counterpart. It serves as a valuable synthetic intermediate and analytical standard for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Deuterated Pharmaceutical Intermediate: Used in the synthesis of deuterated drug candidates for metabolic stability studies and as internal standards in bioanalytical methods (LC-MS/MS).
• Agrochemical Research: Acts as a building block for creating labeled pesticide or herbicide analogs to study environmental fate, degradation pathways, and residue analysis.
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions (e.g., Suzuki, Heck) to introduce deuterated aromatic moieties into complex molecules for material science and chemical biology.
• Analytical Reference Standard: Serves as a high-purity certified reference material (CRM) for quantitative NMR (qNMR) and mass spectrometry, ensuring accuracy in analytical measurements.
• Metabolomics & Proteomics: Utilized in the preparation of isotope-labeled probes or tags for the relative and absolute quantification of biomolecules.
• Materials Science: A precursor for synthesizing deuterated organic semiconductors or liquid crystals, where isotopic substitution can modify electronic properties and stability.

Basic Information

Item	Detail
Product Name	m-Nitrophenyl-D4 Bromide
CAS No.	81395-16-6
Molecular Formula	C6D4BrNO2
Molecular Weight	Contact for details
Synonyms	1-Bromo-3-nitrobenzene-D4; 3-Bromonitrobenzene-D4; m-Bromonitrobenzene-D4; 3-Nitrophenyl-D4 Bromide; (2,3,5,6-D4)-3-Bromonitrobenzene; 1-Bromo-3-nitro-(2,3,5,6-D4)benzene; Deuteronitrobenzene-D4 bromide (m-isomer)
EINECS	Contact for details

Quality Control

Every batch of m-Nitrophenyl-D4 Bromide is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to confirm chemical identity, isotopic purity (D-enrichment), and chemical purity. Certificates of Analysis (COA) detailing results from NMR, HPLC, and MS are available for each lot to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (NMR)	Conforms to structure
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Chemical Purity (HPLC)	≥ 97%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.