Description

Pyridine, 3-Ethoxy-4-(Trimethylsilyl)- (9Ci) is a specialized organosilicon-substituted pyridine derivative, serving as a valuable synthetic intermediate and protecting group reagent in advanced organic synthesis. Its unique structure, combining a silyl ether with the pyridine heterocycle, provides distinct reactivity and stability for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries who require high-purity building blocks for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the pyridine-silicon moiety imparts specific biological activity or stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the production of specialty polymers, silicones, and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed in the design of novel organometallic catalysts and ligands for asymmetric synthesis and cross-coupling reactions.
• Protecting Group Chemistry: The trimethylsilyl (TMS) and ethoxy groups can act as protective functionalities for sensitive alcohols or phenols during multi-step syntheses.
• Academic and R&D: Critical reagent for methodological research in organic synthesis, enabling new routes to complex, silicon-containing molecules.

Basic Information

Product Name	Pyridine, 3-Ethoxy-4-(Trimethylsilyl)- (9Ci)
CAS No.	81376-87-6
Molecular Formula	C10H17NOSi
Molecular Weight	195.34 g/mol
Synonyms	3-Ethoxy-4-(trimethylsilyl)pyridine; 4-(Trimethylsilyl)-3-ethoxypyridine; 3-Ethoxy-4-trimethylsilylpyridine; Pyridine, 3-ethoxy-4-(trimethylsilyl)-; 3-Ethoxy-4-pyridyltrimethylsilane; (3-Ethoxy-4-pyridyl)trimethylsilane
EINECS	Contact for details

Quality Control

Our production of Pyridine, 3-Ethoxy-4-(Trimethylsilyl)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.