Description

1-(2,3-Dihydro-3-(4-Morpholinylmethyl)-2-Oxo-5-Benzoxazolyl)-2,5-Pyrro Lidinedione is a high-purity, specialized heterocyclic organic compound featuring a benzoxazolone core fused with a pyrrolidinedione moiety and a morpholinylmethyl substituent. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate for the research and development of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules. The compound's structural complexity offers significant potential for creating targeted drug candidates with specific biological activities.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential new chemical entities (NCEs) for drug discovery programs.
• Protease Inhibitor Research: Used in the development of enzyme inhibitors, leveraging its heterocyclic structure to interact with active sites.
• Neurological & CNS Drug Development: Investigated as a precursor for compounds targeting neurological disorders due to its ability to cross the blood-brain barrier.
• Oncology Research: Employed in the synthesis of experimental anti-cancer agents designed to induce apoptosis or inhibit tumor growth.
• Chemical Biology & Probe Development: Utilized to create molecular probes for studying biological pathways and protein functions.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Used in university and institutional laboratories for fundamental studies in medicinal chemistry and organic synthesis.

Basic Information

Product Name	1-(2,3-Dihydro-3-(4-Morpholinylmethyl)-2-Oxo-5-Benzoxazolyl)-2,5-Pyrro Lidinedione
CAS No.	81282-54-4
Molecular Formula	C₁₈H₂₁N₃O₅
Molecular Weight	359.38 g/mol
Synonyms	1-(3-(Morpholin-4-ylmethyl)-2-oxo-2,3-dihydro-1,3-benzoxazol-5-yl)pyrrolidine-2,5-dione; 5-(2,5-Dioxopyrrolidin-1-yl)-3-(morpholin-4-ylmethyl)-1,3-benzoxazol-2(3H)-one; 1-[3-(4-Morpholinylmethyl)-2-oxo-5-benzoxazolyl]-2,5-pyrrolidinedione; 81282-54-4; 1-(3-(Morpholinomethyl)-2-oxo-2,3-dihydrobenzoxazol-5-yl)pyrrolidine-2,5-dione; 5-(2,5-Dioxo-1-pyrrolidinyl)-3-(4-morpholinylmethyl)-2(3H)-benzoxazolone; Benzoxazolone-morpholine-pyrrolidinedione derivative.
EINECS	Contact for details

Quality Control

Our production of 1-(2,3-Dihydro-3-(4-Morpholinylmethyl)-2-Oxo-5-Benzoxazolyl)-2,5-Pyrro Lidinedione adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research applications. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We employ advanced analytical techniques including HPLC, NMR, and MS to verify the chemical structure and meet the exacting standards required for pharmaceutical R&D. Certificates of Analysis are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if specified. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.