Description

1H-Benz(De)Isoquinoline-2(3H)-Acetamide, α-(4-Aminobutyl)-1,3-Diox o-n-Tricyclo(3.3.1.1(3,7))Dec-1-Yl-, Monohydrobromide is a specialized organic salt with a complex, polycyclic structure, making it a valuable intermediate for advanced chemical synthesis. Its primary commercial value lies in its role as a high-purity building block for pharmaceutical research and development, particularly in the creation of novel active pharmaceutical ingredients (APIs). This compound is essential for R&D chemists and process development scientists working in medicinal chemistry, agrochemicals, and advanced material science.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those targeting neurological or receptor-specific pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its unique fused ring system and functional groups.
• Agrochemical Development: Serves as a precursor for novel crop protection agents and pesticides requiring specific stereochemistry.
• Chemical Biology Probes: Utilized in the development of fluorescent tags or molecular probes for studying biological systems.
• Advanced Material Synthesis: Potential monomer or precursor for specialty polymers and organic electronic materials.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis projects and scale-up development.

Basic Information

Product Name	1H-Benz(De)Isoquinoline-2(3H)-Acetamide, α-(4-Aminobutyl)-1,3-Diox o-n-Tricyclo(3.3.1.1(3,7))Dec-1-Yl-, Monohydrobromide
CAS No.	81274-66-0
Molecular Formula	C24H33N3O3·HBr
Molecular Weight	Contact for details
Synonyms	1H-Benz[de]isoquinoline-2(3H)-acetamide, α-(4-aminobutyl)-1,3-dioxo-n-tricyclo[3.3.1.13,7]dec-1-yl-, monohydrobromide; Adamantane-linked isoquinoline acetamide HBr salt; N-[(1,3-Dioxo-2-adamantyl)butyl]-1H-benz[de]isoquinoline-2(3H)-acetamide hydrobromide; 81274-66-0; Tricyclo[3.3.1.13,7]decane-1-acetamide derivative HBr salt
EINECS	Contact for details

Quality Control

Our 1H-Benz(De)Isoquinoline-2(3H)-Acetamide, α-(4-Aminobutyl)-1,3-Diox o-n-Tricyclo(3.3.1.1(3,7))Dec-1-Yl-, Monohydrobromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.