Description

Pyrano(2,3-G)Indole-2-Carboxylic Acid, 1,7,8,9-Tetrahydro-5-Methoxy-9- Oxo- is a high-purity, complex heterocyclic carboxylic acid derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmacophore and versatile synthetic building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and specialty chemical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex alkaloid analogs and potential therapeutic agents targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Organic Synthesis Building Block: Employed in cyclization reactions and as a starting material for constructing fused polycyclic systems due to its reactive indole and pyranone moieties.
• Biochemical Research: Potential use as a reference standard or inhibitor in enzymatic studies, given its structural similarity to certain natural product inhibitors.
• Fine Chemical Production: Serves as an intermediate in the multi-step synthesis of dyes, pigments, or advanced materials with specific optical properties.

Basic Information

Product Name	Pyrano(2,3-G)Indole-2-Carboxylic Acid, 1,7,8,9-Tetrahydro-5-Methoxy-9- Oxo-
CAS No.	81258-05-1
Molecular Formula	C₁₃H₁₁NO₅
Molecular Weight	261.23 g/mol
Synonyms	1,7,8,9-Tetrahydro-5-methoxy-9-oxopyrano[2,3-g]indole-2-carboxylic acid; 9-Oxo-1,7,8,9-tetrahydro-5-methoxypyrano[2,3-g]indole-2-carboxylic acid; Pyrano[2,3-g]indole-2-carboxylic acid, 1,7,8,9-tetrahydro-5-methoxy-9-oxo-; 5-Methoxy-9-oxo-1,7,8,9-tetrahydro-2H-pyrano[2,3-g]indole-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of Pyrano(2,3-G)Indole-2-Carboxylic Acid, 1,7,8,9-Tetrahydro-5-Methoxy-9- Oxo- adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested against comprehensive specifications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support development and commercial projects requiring material that meets GMP-grade standards for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to exclude moisture and prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.