Description

1,7,8,9-Tetrahydro-5-Chloropyrano(2,3-G)Indole-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex fused-ring structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) and serves as a key building block in modern medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within the fields of oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of complex drug candidates and novel APIs.
• Medicinal Chemistry Research: Serves as a sophisticated scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Used in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.
• Bioconjugation & Probe Development: Potential use in creating labeled compounds or molecular probes for biochemical and diagnostic research.

Basic Information

Product Name	1,7,8,9-Tetrahydro-5-Chloropyrano(2,3-G)Indole-2-Carboxylic Acid
CAS No.	81257-91-2
Molecular Formula	C15H12ClNO3
Molecular Weight	289.71 g/mol
Synonyms	5-Chloro-1,7,8,9-tetrahydropyrano[2,3-g]indole-2-carboxylic acid; 5-Chloro-2-carboxy-1,7,8,9-tetrahydropyrano[2,3-g]indole; 81257-91-2; Pyranoindole-2-carboxylic acid derivative; Tetrahydrochloropyranoindolecarboxylic acid
EINECS	Contact for details

Quality Control

Our production of 1,7,8,9-Tetrahydro-5-Chloropyrano(2,3-G)Indole-2-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We operate under a quality system designed to meet the expectations of GMP (Good Manufacturing Practice) guidelines for advanced intermediates, ensuring traceability and documentation for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.