Description

5-Bromo-1,2,3,4-Tetrahydro-Isoquinoline Hydrochloride is a versatile and high-value synthetic building block, primarily utilized in advanced pharmaceutical research and development. Its core value lies in its role as a key precursor for synthesizing complex molecules with potential biological activity, offering researchers a reliable and high-purity starting material. This compound is essential for medicinal chemists and process development scientists working in pharmaceutical, agrochemical, and fine chemical industries, particularly in the development of central nervous system (CNS) and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of new active ingredients for crop protection products.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and advanced materials.
• Academic & Institutional Research: A valuable reagent for universities and research institutes studying heterocyclic chemistry and organic synthesis methodologies.
• Process Chemistry Development: Used for scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.

Basic Information

Product Name	5-Bromo-1,2,3,4-Tetrahydro-Isoquinoline Hydrochloride
CAS No.	81237-69-6
Molecular Formula	C9H10BrN•HCl
Molecular Weight	248.55 g/mol
Synonyms	5-Bromo-1,2,3,4-tetrahydroisoquinoline HCl; 5-Bromo-1,2,3,4-tetrahydroisoquinoline hydrochloride; 5-Bromotetrahydroisoquinoline hydrochloride; 1,2,3,4-Tetrahydro-5-bromoisoquinoline hydrochloride; 5-Bromo-THIQ•HCl; 5-Br-THIQ HCl; Isoquinoline, 5-bromo-1,2,3,4-tetrahydro-, hydrochloride
EINECS	Contact for details

Quality Control

Our 5-Bromo-1,2,3,4-Tetrahydro-Isoquinoline Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, residual solvent analysis, and identity confirmation. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.