Description

(S,E)-4-Phenyl-3-Butene-2-Ol CAS NO 81176-43-4 is a chiral, unsaturated alcohol that serves as a valuable intermediate in fine chemical synthesis. Its defined stereochemistry and functional group array make it a critical building block for creating complex molecules with high optical purity. This compound is essential for research and production in the pharmaceutical and advanced materials sectors, where precise molecular architecture dictates performance.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in routes requiring stereochemical control.
• Agrochemical Synthesis: Used in the production of advanced, optically active pesticides and herbicides.
• Liquid Crystal & OLED Materials: Serves as a precursor for organic electronic materials due to its conjugated phenyl-butene structure.
• Flavor & Fragrance Industry: Intermediate for the synthesis of specific aroma chemicals where the (S,E)-configuration imparts desired olfactory characteristics.
• Asymmetric Catalysis Research: A valuable test substrate or ligand precursor in the development of new chiral catalysts.
• Specialty Polymer Modification: Used to introduce chiral centers or phenyl groups into polymer backbones for specialized material properties.

Basic Information

Product Name	(S,E)-4-Phenyl-3-Butene-2-Ol
CAS No.	81176-43-4
Molecular Formula	C10H12O
Molecular Weight	148.20 g/mol
Synonyms	(S,E)-4-Phenyl-3-buten-2-ol; (S,E)-4-Phenylbut-3-en-2-ol; (2S,3E)-4-Phenyl-3-buten-2-ol; (S)-(-)-4-Phenyl-3-buten-2-ol; (S,E)-4-Phenyl-3-buten-2-ol; Phenylbutenol; (S,E)-Phenylbutenol; Chiral Phenylbutenol
EINECS	Contact for details

Quality Control

Every batch of (S,E)-4-Phenyl-3-Butene-2-Ol is produced under strict quality management protocols. We employ advanced analytical techniques, including chiral HPLC, GC, and NMR, to ensure high enantiomeric and chemical purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee consistency and traceability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider an inert atmosphere to preserve optimal quality.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.