Description

8-Chloro-Tetrahydroisoquinoline-7-Sulfonamide is a high-purity, specialized heterocyclic sulfonamide building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which serves as a critical precursor for the development of novel pharmacologically active compounds. This intermediate is primarily needed by research and development teams within the pharmaceutical and agrochemical industries, where it is utilized to construct complex molecules for drug discovery and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential therapeutic agents, particularly those targeting central nervous system (CNS) disorders, cardiovascular diseases, and enzyme inhibition.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its sulfonamide moiety for biological activity.
• Chemical Biology Probe Synthesis: Serves as a scaffold for creating molecular probes to study biological pathways and protein functions.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex tetrahydroisoquinoline derivatives and sulfonamide libraries.
• Material Science Precursor: Potential use in the synthesis of specialized organic materials and ligands for catalytic systems.

Basic Information

Product Name	8-Chloro-Tetrahydroisoquinoline-7-Sulfonamide
CAS No.	81134-73-8
Molecular Formula	C9H11ClN2O2S
Molecular Weight	246.71 g/mol
Synonyms	8-Chloro-1,2,3,4-tetrahydroisoquinoline-7-sulfonamide; 7-Sulfamoyl-8-chloro-1,2,3,4-tetrahydroisoquinoline; 8-Chloro-7-sulfonamidotetrahydroisoquinoline; 8-Chloro-THIQ-7-sulfonamide; 8-Cl-THIQ-7-SO2NH2
EINECS	Contact for details

Quality Control

Our 8-Chloro-Tetrahydroisoquinoline-7-Sulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and process development. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.