Description

1-Chloro-3,5-Dibromo-2-Iodobenzene is a highly functionalized halogenated benzene derivative, serving as a critical multi-halogenated synthon in advanced organic synthesis. Its unique substitution pattern makes it a versatile and valuable building block for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is essential for chemists and R&D teams in fine chemical, pharmaceutical, and material science industries who require precise halogenated intermediates for coupling reactions and the development of novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially those requiring specific halogen substitution for bioactivity or as a handle for further functionalization.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides where halogenated aromatic rings are common structural motifs.
• Material Science: Serves as a monomer or building block for creating specialized polymers, liquid crystals, or organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for various palladium-catalyzed reactions (e.g., Suzuki, Stille, Sonogashira) due to the presence of iodine and bromine, which have distinct reactivity profiles.
• Ligand Synthesis: Utilized in the preparation of sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A valuable tool in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Product Name	1-Chloro-3,5-Dibromo-2-Iodobenzene
CAS No.	81067-45-0
Molecular Formula	C6H2Br2ClI
Molecular Weight	436.24 g/mol
Synonyms	2-Iodo-1-chloro-3,5-dibromobenzene; 3,5-Dibromo-2-iodo-1-chlorobenzene; 1-Chloro-3,5-dibromo-2-iodobenzene; Benzene, 1-chloro-3,5-dibromo-2-iodo-; Chlorodibromoidobenzene
EINECS	Contact for details

Quality Control

Our 1-Chloro-3,5-Dibromo-2-Iodobenzene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We employ advanced analytical techniques including HPLC, GC, and NMR for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.