Description

Octahydro-1H-Indole-2-Carboxylic Acid is a saturated bicyclic organic compound featuring both indoline and carboxylic acid functional groups, making it a versatile chiral building block. This high-purity intermediate is critical for synthesizing complex molecules with precise stereochemistry. It is primarily utilized by pharmaceutical R&D and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs) and advanced agrochemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of protease inhibitors, neurological agents, and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides with specific stereochemical requirements.
• Asymmetric Catalysis: Serves as a precursor or ligand for chiral catalysts used in stereoselective chemical transformations.
• Peptidomimetics Research: Employed in medicinal chemistry to create conformationally constrained peptide analogs for drug discovery.
• Fine Chemical Production: A building block for specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.

Basic Information

Product Name	Octahydro-1H-Indole-2-Carboxylic Acid
CAS No.	80828-13-3
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	Hexahydro-1H-indole-2-carboxylic acid (perhydro form); 2-Carboxyhexahydroindole; Octahydroindole-2-carboxylic acid; (RS)-Octahydro-1H-indole-2-carboxylic acid; Perhydroindole-2-carboxylic acid; 1,2,3,3a,4,5,6,7-Octahydroindole-2-carboxylic acid; 2-Indolinecarboxylic acid, hexahydro-
EINECS	Contact for details

Quality Control

Our Octahydro-1H-Indole-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) with full chromatographic data is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee (by Chiral HPLC)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.