Description

Phosphorylleucylphenylalanine CAS NO 80826-98-8 is a specialized synthetic peptide derivative, specifically a phosphorylated dipeptide analog. This compound is of significant interest in biochemical research and pharmaceutical development due to its role in studying enzyme kinetics, signal transduction pathways, and protein-protein interactions. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on kinase and phosphatase activity, metabolic studies, and the development of novel therapeutic agents.

Application

• Biochemical Research: As a substrate or inhibitor analog in enzymatic assays for studying protein kinases and phosphatases.
• Pharmaceutical R&D: A key intermediate or reference standard in the development of peptide-based drugs targeting specific cellular signaling pathways.
• Proteomics & Metabolomics: Used as a standard or probe in mass spectrometry and chromatography to identify and quantify phosphorylated peptides in complex biological samples.
• Cell Signaling Studies: Employed to investigate intracellular signal transduction mechanisms related to growth, differentiation, and apoptosis.
• Academic Research: A valuable tool for universities and research institutes exploring peptide chemistry, phosphorylation dynamics, and metabolic regulation.

Basic Information

Product Name	Phosphorylleucylphenylalanine
CAS No.	80826-98-8
Molecular Formula	C15H21N2O6P
Molecular Weight	356.31 g/mol
Synonyms	Phospho-Leu-Phe; L-Leucyl-L-phenylalanine phosphate; Phosphoryl-Leu-Phe; N-Phosphoryl-leucylphenylalanine; Leu-Phe phosphate; H-Leu-Phe-OH phosphate ester; Phosphonamidate derivative of Leu-Phe; Phosphorylated Leu-Phe dipeptide
EINECS	Contact for details

Quality Control

Our Phosphorylleucylphenylalanine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and specific tests for residual solvents and moisture content. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.